Proteins

Innovating at the intersection of chemistry, biology, and engineering, Professor Brad Pentelute and the Pentelute Lab at MIT invent new chemistry, platforms, and techniques that might revolutionize therapeutics. Their formula in brief: nature-inspired research that begins at the molecular level, infused with state-of-the-art machine learning and automation, aimed at solving real-world problems. Take, for example, biotechnology’s longstanding protein delivery problem. …

Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds against all possible targets, but doing that kind of screen is prohibitively time-consuming. In recent years, researchers have begun using computational methods to screen those libraries in hopes of …

Biology is a wondrous yet delicate tapestry. At the heart is DNA, the master weaver that encodes proteins, responsible for orchestrating the many biological functions that sustain life within the human body. However, our body is akin to a finely tuned instrument, susceptible to losing its harmony. After all, we’re faced with an ever-changing and relentless natural world: pathogens, viruses, …