National Institutes of Health (NIH)

How an archeological approach can help leverage biased data in AI to improve medicine

The classic computer science adage “garbage in, garbage out” lacks nuance when it comes to understanding biased medical data, argue computer science and bioethics professors from MIT, Johns Hopkins University, and the Alan Turing Institute in a new opinion piece published in a recent edition of the New England Journal of Medicine (NEJM). The rising popularity of artificial intelligence has…

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A better way to match 3D volumes

In computer graphics and computer-aided design (CAD), 3D objects are often represented by the contours of their outer surfaces. Computers store these shapes as “thin shells,” which model the contours of the skin of an animated character but not the flesh underneath. This modeling decision makes it efficient to store and manipulate 3D shapes, but it can lead to unexpected…

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New model offers a way to speed up drug discovery

Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds against all possible targets, but doing that kind of screen is prohibitively time-consuming. In recent years, researchers have begun using computational methods to screen those libraries in hopes of…

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